Does thyroid cancer spread to the uterus?
Differentiated thyroid cancer may very rarely spread to the visceral pelvis (uterus, ovary). Tumor-to-tumor intramyoma uterine metastasis of papillary thyroid carcinoma origin is reported as a very rare dedifferentiated (trabecular) tumor spread of intermediate prognosis.
Is an oncocytic neoplasm cancerous?
The majority of oncocytic neoplasms is considered to be benign and displays low invasiveness. Prognosis of kidney oncocytoma, Warthin tumor and oncocytic pituitary adenoma is in fact usually favourable.
What is oncocytic thyroid cancer?
Oncocytic PDTCs are defined as invasive follicular cell-derived thyroid neoplasms with more than 75% oncocytic change that have solid/trabecular/insular growth in association with increased mitotic activity (>3 per 2mm2) and/or necrosis (Figure 3) (11).
Can thyroid cancer cause endometrial cancer?
Among the risk factors related to endometrial cancer, hypothyroidism interacts with metabolic syndrome, polycystic ovarian syndrome and infertility or directly acts on the endometrium itself, which may influence the development and progression of endometrial cancer.
Is thyroid cancer related to cervical cancer?
Carcinoma of the uterine cervix (cervical cancer) metastasising to the thyroid gland is a rare phenomenon and only a few cases have been reported.
What is oncocytic?
Oncocytic change is defined as cellular enlargement characterised by an abundant eosinophilic granular cytoplasm as a result of the accumulation of altered mitochondria. This is a phenomenon of metaplasia that occurs in inflammatory disorders, such as thyroiditis, or other situations that result in cellular stress.
What is a low grade oncocytic tumor?
Background. The term low-grade oncocytic tumour of kidney is an emerging entity describing CD117-negative and cytokeratin 7-positive indolent tumors with overlapping morphological features between oncocytic tumors.
What does oncocytic mean?
Definition. Oncocytic change is defined as cellular enlargement characterised by an abundant eosinophilic granular cytoplasm as a result of the accumulation of altered mitochondria.
How does thyroid affect uterus?
Both E2 and P4 levels play essential roles in uterine development and the menstrual cycle. Therefore, it was indicated that thyroid hormones might cause menstrual irregularities and influence uterine development by altering the reproductive hormone levels under different thyroid statuses.
Is there a connection between thyroid and ovarian cancer?
Ovarian cancer is known to metastasize to the thyroid gland. Despite an incidence of ovarian metastasis to the thyroid of 3–15%, clinical hypothyroidism resulting from such metastasis has not yet been reported.
Can you have thyroid in your cervix?
Thyroid metastasis from cervical carcinomas is extremely rare; and only a few cases have been previously reported in the literature. In patient with thyroid nodules and an oncological history, the possibility of thyroid metastasis should be seriously considered.
Can thyroid affect your cervix?
Hypothyroidism significantly increased the salt-soluble, acid-soluble, insoluble and total collagen in the uterus and cervix. However, all of these collagens were significantly decreased in the hyperthyroid condition.
What is oncocytic epithelial cells?
An oncocyte is an epithelial cell characterized by an excessive number of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or malignant.
What is low grade oncocytic neoplasm?
Is oncocytoma malignant?
Renal oncocytoma is a noncancerous (benign) growth in one or both of your kidneys. These lesions may not cause symptoms or need treatment.
What causes oncocytic cells?
What is in oncocytic cytoplasm?
Oncocytes are epithelial cells which appear as cells with abundant, granular, eosinophilic cytoplasm, a central pyknotic nucleus, and ultrastructurally are crammed with numerous mitochondria of various sizes.
Can a thyroid be in your uterus?
Our study suggested that uterine fibroids in women were definitely associated with thyroid nodules and estrogen might have a pivotal role in occurrence of both uterine fibroids and thyroid nodules.
What is an oncocytic nodule in thyroid cancer?
An oncocytic nodule in the setting of chronic lymphocytic thyroiditis may be completely encapsulated and show no evidence of capsular or vascular invasion. In the absence of nuclear features of papillary carcinoma, this would be considered an adenoma.
What do we know about the oncocytic variant of medullary thyroid carcinoma?
Little is known about the molecular alterations that underlie the oncocytic variant in addition to the frequent RETmutations and less common RASmutations that occur in non-oncocytic medullary thyroid carcinomas. Metastatic and Invasive Oncocytic Tumors of Non-Thyroid Origin
What are oncocytic tumours?
Oncocytic tumours are found in the thyroid and other endocrine tissues, including the parathyroid, pituitary, adrenal cortex, pancreas, gut, and lung. Outside of the endocrine system, there is an oncocytic variant of renal cell carcinoma, and salivary glands, particularly the parotid, develop oncocytic nodules and tumours.
What is oncocytic change in parathyroid cancer?
In some circumstances, oncocytic change is a feature of tumours that have a benign behaviour, such as renal cell carcinomas. Parathyroid tumours with oncocytic change were thought to have reduced functional capacity for hormone production.