What is the half-life of yttrium-90?

Yittrium-90 is a pure beta-emitter, with a decay energy of 0.94 MeV and the average penetration depth in human tissue is 2.4 mm. In the form of microspheres, it is suitable for selective arterial injection. The physical half-life of Y-90 is 64.2 h.

How does Y-90 treatment work?

In Y-90 radiotherapy, millions of tiny radioactive beads are injected directly into the arteries that supply blood to your tumor. These beads will stay in the blood vessels around your tumor(s). This allows very strong radiation to reach the tumors directly.

How long are you radioactive after Y-90?

Because radioactive microspheres are delivered through the hepatic artery, they reach the tumor very directly while sparing most of the healthy liver tissue. The radiation from yttrium-90 continually decreases over a two-week period and disappears after 30 days.

What type of radiation is Y-90?

Y90 is a pure beta-particle-emitter with a physical half-life of 64.2 hours, 0.94 MeV decay energy, and an average penetrative depth of 2.4mm in human tissue.

Can Y-90 treatment be repeated?

The current study shows that repeat treatment to the same hepatic arterial territory is as safe as single treatment to the same territory.

How long does Y-90 treatment take?

If there are multiple tumors, the procedure may need to be repeated in another blood vessel. The procedure takes about one hour to complete.

Can Y-90 be repeated?

Why is yttrium-90 used in nuclear medicine?

About yttrium-90 This makes it a suitable isotope for Selective Internal Radiation Therapy (SIRT). The treatment is used for indications in the liver: inoperable hepatocellular carcinomas and liver metastases. Y-90 has also been proven to be effective among others in radiosynoviorthesis.

How is yttrium-90 obtained?

Yttrium-90 is produced by the nuclear decay of strontium-90 which has a half-life of nearly 29 years and is a fission product of uranium used in nuclear reactors. As the strontium-90 decays, chemical high-purity separation is used to isolate the yttrium-90 before precipitation.

Can Y90 treatment be repeated?

Is Y90 a brachytherapy?

The Yttrium-90 irradiates from within and can be viewed as “internal” radiation or “brachytherapy.” Radioembolization is a palliative, not a curative, treatment. Patients may benefit by extending their lives and improving their quality of life.

Where is yttrium-90 produced?

What type of radiation is Y90?

What is the most common adverse effect from Radioembolization?

Many people experience symptoms of fatigue, nausea, abdominal pain, fever, and loss of appetite after radioembolization. These effects are usually mild or moderate, and most people leave the hospital within a day or two after the procedure.

What are the side effects of Y90 treatment?

A post-radioembolization syndrome (PRS) includes fatigue, nausea/vomiting, abdominal pain/discomfort, and/or cachexia. PRS is less severe than that observed after embolic therapies.

What is yttrium-90 decay scheme?

Yttrium-90 Decay Scheme Yttrium-90 (90 Y) is a beta (electron) emitter with an average energy of 0.9267 MeV and a half-life of 2.67 days. Over 90% of emitted energy is absorbed within 5.3mm and the maximum range of emitted electons is 11mm. Y-90 is most commonly used in radiation therapy as the source in microsphere liver treatments.

What is yttrium-90 (Y-90) radiotherapy?

Our team of experts believes that Yttrium-90 (Y-90) radiotherapy is the best option for you at this time. Y-90 radiotherapy sends radiation directly into the blood vessels that feed the tumors. This treatment does not cure liver tumors. But, it often controls or shrinks them.

How is yttrium-90 separated from strontium-90?

As the strontium-90 decays, chemical high-purity separation is used to isolate the yttrium-90 before precipitation. 90 Y plays a significant role in the treatment of hepatocellular carcinoma (HCC), leukemia, and lymphoma, although it has the potential to treat a range of tumors.

How do you make yttrium 90?

Production Yttrium-90 is produced by the nuclear decay of strontium-90 which has a half-life of nearly 29 years and is a fission product of uranium used in nuclear reactors. As the strontium-90 decays, chemical high-purity separation is used to isolate the yttrium-90 before precipitation.