What is guaifenesin made from?
Guaifenesin was originally derived from the guaiac tree and used by Native Americans for health purposes. Synthesis of guaifenesin was first reported in 1912. Guaifenesin has been used in the treatment of respiratory diseases since the nineteenth century.
Is guaifenesin toxic?
Overdose with guaifenesin is unlikely to produce toxic effects since its toxicity is low. Very large doses may cause nausea and vomiting. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are using guaifenesin.
Why should guaifenesin be given with a full glass of water?
Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Drink plenty of fluids while taking this medication. Fluids will help to break up mucus and clear congestion.
What type of drug is guaifenesin?
Guaifenesin is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.
Does guaifenesin affect the brain?
At high doses, guaifenesin causes depression of the central nervous system and is used as a muscle relaxant with sedative effects in veterinary medicine (1, 5–7).
Does guaifenesin raise blood pressure?
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth. These medicines are not known to elevate blood pressure.
Does guaifenesin keep you awake at night?
Mucinex D (guaifenesin / pseudoephedrine) is a combination medication containing guaifenesin and pseudoephedrine. They work together to help relieve a stuffy nose and a cough with mucus without causing daytime sleepiness, but it can keep you up at night.
Can guaifenesin raise blood pressure?
Is it OK to take guaifenesin everyday?
Do not take this medication for more than 7 days unless your doctor tells you to do so. Tell your doctor if your condition lasts longer than 7 days. If you miss a dose, take it as soon as you remember.
What is another name for guaifenesin?
Guaifenesin is available under the following different brand names: Mucinex, Bidex 400, and Organidin NR.
Will guaifenesin keep you awake at night?
Can guaifenesin cause anxiety?
Stop using this medicine and call your doctor at once if you have: mood changes; severe headache; or. severe dizziness or anxiety, feeling like you might pass out;.
Can guaifenesin cause depression?
What are side effects of guaifenesin?
- nausea or vomiting.
- skin rash.
- stomach pain.
What is guaiphenesin?
Guaifenesin (International Noproprietary Name) or guaiphenesin (former British Approved Name) is an expectorant drug usually taken orally to assist the expectoration (‘bringing up’) of phlegm from the airways in acute respiratory tract infections. It is a common ingredient in many over-the-counter cough/cold medications.
What are the neurological properties of guaifenesin?
Guaifenesin’s neurological properties first became known in the late 1940s. Guaifenesin is a centrally acting muscle relaxant used routinely in large-animal veterinary surgery. Guaifenesin is used in combination with, for example, ketamine, since guaifenesin does not provide analgesia nor does it produce unconsciousness.
Is guaifenesin a glyceryl guaiacolate?
2005-03-25 Guaifenesin is a glyceryl guaiacolate with expectorant effects. Guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasympathetic reflexes that cause glandular exocytosis.
What is the Koc of guaifenesin?
AQUATIC FATE: Based on a classification scheme (1), an estimated Koc value of 140 (SRC), determined from a log Kow of 1.39 (2) and a regression-derived equation (3), indicates that guaifenesin is not expected to adsorb to suspended solids and sediment (SRC).