What is Cinnarizine 25mg used for?
It’s used for: travel sickness (also called motion sickness) dizziness and sickness caused by inner ear problems (such as vertigo, tinnitus and Ménière’s disease)
What are the side effects of Cinnarizine?
What are the side effects of Cinnarizine? Central Nervous System : Drowsiness, headache, GI upset, unsteadiness, headache, depression dizziness and incoordination. Skin : Rash. Gastrointestinal : Nausea, vomiting, diarrhea or constipation, loss of appetite or increased appetite and stomach pain.
How do you take Cinnarizine 25 mg?
Cinnarizine
- Adult: For symptoms of labyrinthine disorders, including dizziness, vertigo, tinnitus, nystagmus, nausea and vomiting: As tab: 25 mg or 30 mg tid.
- Adult: As cap: 75 mg once daily.
- Adult: As 15 mg tab: Initially, 30 mg to be taken 2 hours before travel, then 15 mg 8 hourly during the journey if necessary.
When should I take Cinnarizine?
One tablet two hours before travel and half a tablet every eight hours during journey if necessary. For oral use. Cinnarizine should preferably be taken after meals. The tablets may be sucked, chewed or swallowed whole with water.
Can I take cinnarizine with high blood pressure?
Most of these side effects of CINNARIZINE do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. CINNARIZINEs should not be taken if you have a peptic ulcer, asthma, low blood pressure.
What is the mechanism of action of cinnarizine?
Cinnarizine, developed as an anti-histamine, subsequently manifested a number of pharmacological effects, most significantly: labyrinthine suppressant action and peripheral anti-vasoconstrictive effects [ 5 ]. Cinnarizine inhibits smooth muscle cell contraction in the vasculature by blocking L-and T-type voltage-gated calcium channel.
Does cinnarizine prevent seasickness in very rough seas?
In a double-blind, placebo-controlled study, we evaluated the effect of two different doses of cinnarizine in the prevention of seasickness in very rough seas. We divided 95 healthy male subjects into 3 groups which received: cinnarizine 50 mg, cinnarizine 25 mg, and placebo. Seasickness susceptibil …
Is cinnarizine good for Vertigo?
Cinnarizine, is approved for nausea, vomiting, motion sickness, inner ear disorders and is considered as first-line pharmacotherapy for management of vertigo. It acts by anti-vasoconstrictor activity, reducing blood viscosity and reducing nystagmus in labyrinth.
How many times a day should I take cinnarizine?
It is usually taken three times daily. If you are taking cinnarizine to prevent travel sickness, take the first dose two hours before you are due to travel. If you are going on a long journey, you can then take further doses every eight hours if needed.