What is a triazole antifungal?

What is a triazole antifungal?

Triazole antifungal drugs are used for the prophylaxis and treatment of invasive fungal disease (IFD) in hematology patients undergoing hematopoietic stem cell transplantation (HSCT), or intensive chemotherapy.

What is the BIS triazole antifungal agent?

Abstract. Fluconazole is a fluorine-substituted, bis-triazole antifungal agent. Its mechanism of action, like that of other azoles, involves interruption of the conversion of lanosterol to ergosterol via binding to fungal cytochrome P-450 and subsequent disruption of fungal membranes.

What are the side effects of antifungal creams?

Side effects of antifungal medicines

  • itching or burning.
  • redness.
  • feeling sick.
  • tummy (abdominal) pain.
  • diarrhoea.
  • a rash.

What are the side effects of fluconazole?

Side Effects

  • Chest tightness.
  • clay-colored stools.
  • difficulty with swallowing.
  • fast heartbeat.
  • hives, itching, or skin rash.
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals.
  • light-colored stools.
  • stomach pain, continuing.

Is triazole acidic or basic?

Chemical Reactivity The NH-protons in N-unsubstituted-1,2,4-triazoles are acidic in nature. The pKa of 1,2,4-triazoles is 10.26. The triazolium ions formed are also prone to nucleophiles. Electrophilic substitution takes place only at nitrogen atoms because of high electron density.

What is triazole antifungal?

A number of triazoles are broad spectrum antifungal agents used as pesticides and pharmaceuticals. They inhibit the biosynthesis of ergosterol, which is an essential component of fungal membranes. Triazole antifungal agents are extensively used.

What is terconazole cream?

Terconazole is a topical and broad spectrum triazole antifungal agent with structural similarities to ketoconazoleWeisberg (1989). It is available for adults as a vaginal cream (2 dosages available) or as a vaginal suppository.

How to use clotrimazole cream?

Clotrimazole is an azole antifungal that works by preventing the growth of fungus. How to use Antifungal Cream Use this medication on the skin only. Clean and thoroughly dry the area to be treated.

Where can I find patient medical information for triazole oral?

Triazole Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD Find patient medical information for Triazole oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.