How many people get a bone marrow transplant each year?

Current estimates of annual numbers of stem cell transplants are about 50,000 worldwide, with growth at a rate of 10-15% per year.

How many allogeneic transplants occur each year?

In 2017, 45,418 transplants were reported in 41,100 patients (first transplant); of these, 18,281 HCT (40%) were allogeneic and 27,137 (60%) autologous (Table 1). When compared with 2016 the total number of transplants increased by 4.1% (3.6% allogeneic HCT and 4.4% autologous HCT) [16].

What are the chances of dying from a bone marrow transplant?

The risk of dying from those complications — mostly due to infections and diseases involving the liver, kidneys and lungs — has fallen from 30% to 11% over the past 25 years.

Is a bone marrow transplant worth it?

Bone marrow transplants can be lifesaving for people with conditions such as lymphoma or leukemia, or when intensive cancer treatment has damaged blood cells. This type of transplant can be an intensive procedure, and recovery can take a long time.

What is the most common complication of bone marrow transplantation?

Bacterial infections are the most common. Viral, fungal and other infections can also occur. Some infections can develop later on, weeks to months after the transplant. Infections can cause extended hospital stay, prevent or delay engraftment, cause organ damage, and may be life threatening.

What are the odds of surviving a bone marrow transplant?

How long can you live after a bone marrow transplant? Understandably, transplants for patients with nonmalignant diseases have a much better success rate with 70% to 90 % survival with a matched sibling donor and 36% to 65% with unrelated donors.

When does a bone marrow transplant fail?

Grafts fail when the body does not accept the new stem cells (the graft). The stem cells that were given do not go into the bone marrow and multiply like they should. Graft failure is more common when the patient and donor are not well matched and when patients get stem cells that have had the T-cells removed.

What are the long-term effects of a bone marrow transplant?

The long-term physiologic effects after allo-BMT include nonmalignant organ or tissue dysfunction; changes in quality of life; infections related to delayed, or abnormal, immune reconstitution; and secondary cancers.

What are the common side effects of a bone marrow transplant?

Stem Cell or Bone Marrow Transplant Side Effects

• Mouth and throat pain.
• Nausea and vomiting.
• Infection.
• Bleeding and transfusions.
• Interstitial pneumonitis and other lung problems.
• Graft-versus-host disease.
• Hepatic veno-occlusive disease (VOD)
• Graft failure.